The 35-year-old returned to his boyhood club Feyenoord in January and plans to say goodbye to a career that saw him win 102 caps for the Netherlands, scoring a record 50 goals in the process.
“When [do] I have to stop? That is probably at the end of this season,” he said.
“I will be 36 years old and will have been a professional for 18 years. From the age of five, I’ve only been involved in football.”
Van Persie spent 11 years in English football, winning an FA Cup, a Golden Boot at the PFA Player of the Year prize at Arsenal before controversially moving to Manchester United in the summer of 2012.
The striker would score 26 goals to propel United to the 2013 Premier League title but struggled after the departure of Sir Alex Ferguson that summer.
He would subsequently join Fenerbahce in 2015 before returning to Feyenoord, from whom he had departed for Arsenal.